GL1X · GenesisL1 explorer

Ligand · FIR

FIR · (2R,4S)-2-aminoformyl-6-fluoro-spiro[chroman-4,4'-imidazolidine]-2',5'-dione

FIR, (2R,4S)-2-aminoformyl-6-fluoro-spiro[chroman-4,4'-imidazolidine]-2',5'-dione (C12 H10 F N3 O4, 279.2 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å…

Component
FIR
Formula
C12 H10 F N3 O4
Class
ligand
Structures
2
PDB entries
1

Binding sites

FIR in 2 structures; the first of them:

  • 1X97 · Crystal structure of Aldose Reductase complexed with 2R4S (Stereoisomer of Fidarestat… · FIR A1320 · binds TRP20, VAL47, TYR48, TRP79, HIS110, TRP111, PHE122, TRP219 and 4 more
  • 1X97 · Crystal structure of aldose reductase complexed with 2R4S (stereoisomer of fidarestat… · FIR A1320 · binds TRP20, VAL47, TYR48, TRP79, HIS110, TRP111, PHE122, TRP219 and 4 more

Residues it binds most

TRP 2, VAL 2, ALA 2, CYS 2, HIS 2, LEU 2, PHE 2, TYR 2 (residue and the binding sites it lines).

Found with

  • NAP · Nadp nicotinamide-adenine-dinucleotide phosphate

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.