FI7 · 2-[[2,2-dimethyl-3-[3-(5-oxidanylpyridin-2-yl)-1,2,4-oxadiazol-5-yl]propanoyl]amino]cyclohexene-1-carboxylic acid

Binding sites

FI7 in 6 structures; the first of them:

• 7XK2 · Cryo-EM Structure of Human Niacin Receptor HCA2-Gi protein complex · FI7 R401 · binds LEU83, LEU104, LEU107, ALA108, ARG111, GLN112, LEU158, THR159 and 12 more
• 8IHF · Cryo-EM structure of HCA2-Gi complex with MK6892 · FI7 R602 · binds LEU83, TYR87, TRP91, LEU104, LEU107, ALA108, ARG111, GLN112 and 14 more
• 8IJD · Cryo-EM structure of human HCAR2-Gi complex with MK-6892 · FI7 A401 · binds TYR87, TRP91, LEU104, LEU107, ALA108, ARG111, GLN112, LEU158 and 11 more
• 8IYH · Structure of MK6892-GPR109A-G-protein complex · FI7 D401 · binds LEU83, TYR87, LEU104, LEU107, ALA108, ARG111, GLN112, LEU158 and 8 more
• 8J6I · Cryo-EM structure of thehydroxycarboxylic acid receptor 2-Gi protein complex bound MK-6892 · FI7 R401 · binds LEU83, TYR87, LEU104, LEU107, ALA108, ARG111, GLN112, LEU158 and 12 more
• 8JZ7 · Cryo-EM structure of MK-6892-bound HCAR2 in complex with Gi protein · FI7 A401 · binds LEU83, TYR87, LEU104, LEU107, ALA108, ARG111, GLN112, THR159 and 9 more

Residues it binds most

LEU 6, SER 6, PHE 6, TYR 6, HIS 6, ALA 6, ARG 6, GLN 6, MET 6, THR 6 (residue and the binding sites it lines).

Found with

• NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose