Ligand · FI4

FI4 · (2S)-1-{[3-(2-chlorophenyl)-6-(2,4-difluorophenoxy)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]amino}propan-2-ol

FI4, (2S)-1-{[3-(2-chlorophenyl)-6-(2,4-difluorophenoxy)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]amino}propan-2-ol (C20 H16 Cl F2 N5 O2, 431.8 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site…

Component: FI4
Formula: C20 H16 Cl F2 N5 O2
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

FI4 in 2 structures; the first of them:

3FI4 · P38 kinase crystal structure in complex with RO4499 · FI4 A361 · binds VAL30, SER32, GLY33, ALA34, VAL38, ALA51, VAL52, LYS53 and 17 more
3FI4 · P38 kinase crystal structure in complex with RO4499 · FI4 A361 · binds VAL30, SER32, GLY33, ALA34, VAL38, ALA51, VAL52, LYS53 and 17 more

Residues it binds most

LEU 2, ALA 2, VAL 2, ASP 2, GLY 2, SER 2, ASN 2, HIS 2, ILE 2, LYS 2 (residue and the binding sites it lines).

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