FI3 · N-[4-({[(2,6-dichloro-3,5-dimethoxyphenyl)carbamoyl](6-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino}methyl)phenyl]propanamide

Binding sites

FI3 in 4 structures; the first of them:

• 4R5S · Crystal structure of EGFR 696-1022 L858R in complex with FIIN-3 · FI3 A1101 · binds LEU718, VAL726, ALA743, LYS745, ILE759, GLU762, MET766, LEU788 and 13 more
• 4R6V · Crystal Structure of FGF Receptor (FGFR) 4 Kinase Harboring the V550L Gate-Keeper… · FI3 A801 · binds LEU473, GLY474, GLU475, GLY476, CYS477, PHE478, VAL481, ALA501 and 17 more
• 4R5S · Crystal structure of EGFR 696-1022 L858R in complex with fiin-3 · FI3 A1101 · binds LEU718, VAL726, ALA743, LYS745, ILE759, GLU762, MET766, LEU788 and 13 more
• 4R6V · Crystal structure of FGF receptor (fgfr) 4 kinase harboring the V550L gate-keeper… · FI3 A801 · binds LEU473, GLY474, GLU475, GLY476, CYS477, PHE478, VAL481, ALA501 and 17 more

Residues it binds most

LEU 4, ALA 4, GLU 4, GLY 4, ASP 4, CYS 4, MET 4, PHE 4, ILE 4, LYS 4 (residue and the binding sites it lines).

Found with

• SO4 · Sulfate ion