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Ligand · FHA

FHA · 2'-deoxy-5'-O-[(S)-{(S)-fluoro[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}(hydroxy)phosphoryl]adenosine

FHA, 2'-deoxy-5'-O-[(S)-{(S)-fluoro[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}(hydroxy)phosphoryl]adenosine (C11 H17 F N5 O11 P3, 507.2 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site…

Component
FHA
Formula
C11 H17 F N5 O11 P3
Class
ligand
Structures
2
PDB entries
1

Binding sites

FHA in 2 structures; the first of them:

  • 3TFS · Ternary complex structure of DNA polymerase beta with a gapped DNA substrate and a, b… · FHA A338 · binds ARG149, GLY179, SER180, ARG183, SER188, GLY189, ASP190, ASP192 and 12 more
  • 3TFS · Ternary complex structure of DNA polymerase beta with a gapped DNA substrate and a, B… · FHA A338 · binds ARG149, GLY179, SER180, ARG183, SER188, GLY189, ASP190, ASP192 and 12 more

Residues it binds most

ASP 2, ARG 2, GLY 2, SER 2, ASN 2, DC 2, DG 2, DT 2, PHE 2, THR 2 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion
  • NA · Sodium ion
  • CL · Chloride ion

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