Ligand · FH0
FH0 · ~{N}-[4-(4-methylpiperazin-1-yl)phenyl]-4-(2-pyridin-3-yl-6,7-dihydro-4~{H}-pyrazolo[5,1-c][1,4]oxazin-3-yl) pyrimidin-2-amine
FH0, ~{N}-[4-(4-methylpiperazin-1-yl)phenyl]-4-(2-pyridin-3-yl-6,7-dihydro-4~{H}-pyrazolo[5,1-c][1,4]oxazin-3-yl) pyrimidin-2-amine (C26 H28 N8 O, 468.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…
- Component
- FH0
- Formula
- C26 H28 N8 O
- Class
- ligand
- Structures
- 2
- PDB entries
- 1
Binding sites
FH0 in 2 structures; the first of them:
- 7C3G · Crystal structure of human ALK2 kinase domain with R206H mutation in complex with a… · FH0 A501 · binds VAL214, TYR219, VAL222, ALA233, LYS235, LEU263, LEU281, THR283 and 11 more
- 7C3G · Crystal structure of human ALK2 kinase domain with R206H mutation in complex with a… · FH0 A501 · binds VAL214, TYR219, VAL222, ALA233, LYS235, LEU263, LEU281, THR283 and 10 more
Residues it binds most
LEU 4, HIS 4, LYS 4, VAL 4, TYR 4, ALA 4, ASP 4, GLU 4, GLY 4, MET 4 (residue and the binding sites it lines).
Found with
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