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Ligand · FFQ

FFQ · [(1R)-1-hydroxypropyl]phosphonic acid

FFQ, [(1R)-1-hydroxypropyl]phosphonic acid (C3 H9 O4 P, 140.1 g/mol), in the MolNFT structures on GenesisL1: bound in 13 records (7 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands…

Component
FFQ
Formula
C3 H9 O4 P
Class
ligand
Structures
13
PDB entries
7

Binding sites

FFQ in 13 structures; the first of them:

  • 1UAE · Structure of udp-N-acetylglucosamine enolpyruvyl transferase · FFQ A421 · binds LYS22, ASN23, ASP49, ARG91, GLY113, GLY114, CYS115, ILE117 and 5 more
  • 3KR6 · MurA dead-end complex with fosfomycin · FFQ A500 · binds LYS22, ASN23, ASP49, ARG91, GLY114, CYS115, ILE117, ARG120 and 4 more
  • 3LTH · E. cloacae MurA dead-end complex with UNAG and fosfomycin · FFQ A500 · binds LYS22, ASN23, ASP49, ARG91, GLY114, CYS115, ILE117, ARG120 and 4 more
  • 3VCY · Structure of MurA (UDP-N-acetylglucosamine enolpyruvyl transferase), from Vibrio fischeri… · FFQ A500 · binds ARG92, GLY115, CYS116, ARG121, THR369, ASP370, HIS395, ARG398
  • 4J1W · Crystal Structure of Fe(II)-HppE with alternative substrate (R)-1-HPP · FFQ A202 · binds ARG97, TYR103, TYR105, VAL122, ASN135, HIS138, GLU142, LEU144 and 5 more
  • 4R7U · Structure of UDP-N-acetylglucosamine 1-carboxyvinyltransferase from Vibrio cholerae in… · FFQ A502 · binds VAL88, THR90, MET91, ARG92, GLY115, CYS116, ALA117, ARG121 and 1 more
  • 7TB0 · E. faecium MurAA in complex with fosfomycin and UNAG · FFQ A502 · binds LYS22, ASN23, ASP50, ARG95, GLY118, CYS119, ILE121, ARG124 and 4 more
  • 1UAE · Structure of udp-N-acetylglucosamine enolpyruvyl transferase · FFQ A421 · binds LYS22, ASN23, ASP49, ARG91, GLY113, GLY114, CYS115, ILE117 and 5 more
  • 3KR6 · Mura dead-end complex with fosfomycin · FFQ A500 · binds LYS22, ASN23, ASP49, ARG91, GLY114, CYS115, ILE117, ARG120 and 4 more
  • 3LTH · E. cloacae mura dead-end complex with unag and fosfomycin · FFQ A500 · binds LYS22, ASN23, ASP49, ARG91, GLY114, CYS115, ILE117, ARG120 and 4 more
  • 3VCY · Structure of mura (udp-N-acetylglucosamine enolpyruvyl transferase), from vibrio fischeri… · FFQ A500 · binds ARG92, GLY115, CYS116, ARG121, THR369, ASP370, HIS395, ARG398
  • 4J1W · Crystal structure of FE(II)-hppe with alternative substrate (R)-1-hpp · FFQ A202 · binds ARG97, TYR103, TYR105, VAL122, ASN135, HIS138, GLU142, LEU144 and 5 more
  • 4R7U · Structure of udp-N-acetylglucosamine 1-carboxyvinyltransferase from vibrio cholerae in… · FFQ A502 · binds VAL88, THR90, MET91, ARG92, GLY115, CYS116, ALA117, ARG121 and 1 more

Residues it binds most

ARG 32, ASP 16, CYS 26, GLY 22, LEU 16, ALA 16, ASN 16, ILE 16, LYS 16, HIS 8 (residue and the binding sites it lines).

Found with

  • UD1 · Uridine-diphosphate-N-acetylglucosamine
  • GOL · Glycerol
  • NA · Sodium ion
  • FE2 · Fe (II) ion
  • PO4 · Phosphate ion
  • PG4 · Tetraethylene glycol
  • K · Potassium ion
  • CL · Chloride ion

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