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Ligand · FDJ

FDJ · 5'-O-[(R)-{[(R)-[(R)-chloro(phosphono)methyl](hydroxy) phosphoryl]oxy}(hydroxy)phosphoryl]thymidine

FDJ, 5'-O-[(R)-{[(R)-[(R)-chloro(phosphono)methyl](hydroxy) phosphoryl]oxy}(hydroxy)phosphoryl]thymidine (C11 H18 Cl N2 O13 P3, 514.6 g/mol), in the MolNFT structures on GenesisL1: bound in 3 records (2 PDB entries). Every binding site…

Component
FDJ
Formula
C11 H18 Cl N2 O13 P3
Class
ligand
Structures
3
PDB entries
2

Binding sites

FDJ in 3 structures; the first of them:

  • 6CTM · Ternary complex crystal structure of DNA polymerase Beta with a dideoxy terminated primer… · FDJ A402 · binds DA6, DG7, DOC10, ARG149, GLY179, SER180, ARG183, SER188 and 10 more
  • 6CTL · Ternary complex crystal structure of DNA polymerase beta with a dideoxy terminated primer… · FDJ A406 · binds DA6, DOC10, GLY179, SER180, ARG183, SER188, GLY189, ASP190 and 8 more
  • 6CTM · Ternary complex crystal structure of DNA polymerase beta with a dideoxy terminated primer… · FDJ A402 · binds DA6, DG7, DOC10, ARG149, GLY179, SER180, ARG183, SER188 and 10 more

Residues it binds most

ASP 3, GLY 3, SER 3, ARG 3, ASN 3, DA 3, DOC 3, PHE 3, THR 3, TYR 3 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion
  • NA · Sodium ion
  • CL · Chloride ion

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