Ligand · F9J

F9J · 5-fluoro-4-[(1S)-1-(5-fluoropyrimidin-2-yl)ethoxy]-N-(5-methyl-1H-pyrazol-3-yl)-6-morpholino-pyrimidin-2-amine

F9J, 5-fluoro-4-[(1S)-1-(5-fluoropyrimidin-2-yl)ethoxy]-N-(5-methyl-1H-pyrazol-3-yl)-6-morpholino-pyrimidin-2-amine (C18 H20 F2 N8 O2, 418.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding…

Component: F9J
Formula: C18 H20 F2 N8 O2
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

F9J in 2 structures; the first of them:

3ZMM · Inhibitors of Jak2 Kinase domain · F9J A2133 · binds GLN853, LEU855, GLY856, VAL863, MET865, ALA880, VAL911, MET929 and 13 more
3ZMM · Inhibitors of JAK2 kinase domain · F9J A2133 · binds GLN853, LEU855, GLY856, VAL863, MET865, ALA880, VAL911, MET929 and 13 more

Residues it binds most

GLY 4, LEU 4, VAL 4, MET 4, TYR 4, ALA 4, ARG 4, ASN 4, ASP 4, GLU 4 (residue and the binding sites it lines).

Found with

ACE · Acetyl group

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