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Ligand · F8B

F8B · ~{N}-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-2-(4-propan-2-yl-1,2,3-triazol-1-yl)ethanamide

F8B, ~{N}-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-2-(4-propan-2-yl-1,2,3-triazol-1-yl)ethanamide (C23 H24 N6 O4, 448.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (2 PDB entries). Every binding site with its…

Component
F8B
Formula
C23 H24 N6 O4
Class
ligand
Structures
2
PDB entries
2

Binding sites

F8B in 2 structures; the first of them:

  • 6GQL · Crystal structure of human C-kit kinase domain in complex with AZD3229-analogue (compound… · F8B A1001 · binds LEU595, VAL603, ALA621, LYS623, GLU640, LEU644, LEU647, ILE653 and 12 more
  • 6GQQ · Crystal structure of human kdr (VEGFR2) kinase domain in complex with AZD3229-analogue… · F8B A1201 · binds LEU840, VAL848, ALA866, LYS868, GLU885, LEU889, ILE892, VAL899 and 11 more

Residues it binds most

LEU 3, CYS 3, VAL 3, GLU 3, ILE 3, LYS 3, PHE 3, ALA 3, ASP 3, GLY 3 (residue and the binding sites it lines).

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