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Ligand · F6M

F6M · N-[(2S)-1-[5-[2-[(4-cyanophenyl)amino]-4-(propylamino) pyrimidin-5-yl]pent-4-ynylamino]-1-oxidanylidene-propan-2-yl]-4-(dimethylamino)-N-methyl-but-2-enamide

F6M, N-[(2S)-1-[5-[2-[(4-cyanophenyl)amino]-4-(propylamino) pyrimidin-5-yl]pent-4-ynylamino]-1-oxidanylidene-propan-2-yl]-4-(dimethylamino)-N-methyl-but-2-enamide (C29 H38 N8 O2, 530.7 g/mol), in the MolNFT structures on GenesisL1: bound…

Component
F6M
Formula
C29 H38 N8 O2
Class
ligand
Structures
1
PDB entries
1

Binding sites

F6M in 1 structure; the first of them:

  • 5X02 · Crystal structure of the FLT3 kinase domain bound to the inhibitor ff- 10101 · F6M A1001 · binds LEU616, VAL624, ALA642, LYS644, VAL675, PHE691, GLU692, TYR693 and 9 more

Residues it binds most

CYS 1, LEU 1, PHE 1, TYR 1, VAL 1, ALA 1, ASP 1, GLU 1, GLY 1, HIS 1 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion

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