Ligand · F4U
F4U · 2-[(3~{S})-2,6-bis(oxidanylidene)piperidin-3-yl]-5-oxidanyl-isoindole-1,3-dione
F4U, 2-[(3~{S})-2,6-bis(oxidanylidene)piperidin-3-yl]-5-oxidanyl-isoindole-1,3-dione (C13 H10 N2 O5, 274.2 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å…
- Component
- F4U
- Formula
- C13 H10 N2 O5
- Class
- ligand
- Structures
- 2
- PDB entries
- 1
Binding sites
F4U in 2 structures; the first of them:
- 7BQV · Cereblon in complex with SALL4 and (S)-5-hydroxythalidomide · F4U A501 · binds ASN351, PRO352, HIS353, GLU377, HIS378, SER379, TRP380, TRP386 and 8 more
- 7BQV · Cereblon in complex with SALL4 and (S)-5-hydroxythalidomide · F4U A501 · binds ASN351, PRO352, HIS353, GLU377, HIS378, SER379, TRP380, TRP386 and 8 more
Residues it binds most
TRP 2, CYS 2, HIS 2, SER 2, VAL 2, ASN 2, GLU 2, GLY 2, PHE 2, PRO 2 (residue and the binding sites it lines).
Found with
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