Ligand · F49
F49 · [2,4-dioxo-3-(2,3,4,5-tetrabromo-6-methoxybenzyl)-3,4-dihydropyrimidin-1(2H)-yl]acetic acid
F49, [2,4-dioxo-3-(2,3,4,5-tetrabromo-6-methoxybenzyl)-3,4-dihydropyrimidin-1(2H)-yl]acetic acid (C14 H10 Br4 N2 O5, 605.9 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its…
- Component
- F49
- Formula
- C14 H10 Br4 N2 O5
- Class
- ligand
- Structures
- 4
- PDB entries
- 2
Binding sites
F49 in 4 structures; the first of them:
- 4XZI · Crystal structure of human Aldose Reductase complexed with NADP+ and JF0049 · F49 A402 · binds TRP20, VAL47, TYR48, TRP79, HIS110, TRP111, PHE115, PHE122 and 6 more
- 4XZL · Crystal structure of human AKR1B10 complexed with NADP+ and JF0049 · F49 X402 · binds TRP21, VAL48, TYR49, TRP80, HIS111, TRP112, PHE116, PHE123 and 7 more
- 4XZI · Crystal structure of human aldose reductase complexed with NADP+ and JF0049 · F49 A402 · binds TRP20, VAL47, TYR48, TRP79, HIS110, TRP111, PHE115, PHE122 and 6 more
- 4XZL · Crystal structure of human AKR1B10 complexed with NADP+ and JF0049 · F49 X402 · binds TRP21, VAL48, TYR49, TRP80, HIS111, TRP112, PHE116, PHE123 and 7 more
Residues it binds most
TRP 4, PHE 4, CYS 4, LEU 4, HIS 4, TYR 4, VAL 4, ALA 2, ARG 2, GLN 2 (residue and the binding sites it lines).
Found with
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