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Ligand · F3A

F3A · 2'-deoxy-5'-O-[(S)-{difluoro[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}(hydroxy)phosphoryl]adenosine

F3A, 2'-deoxy-5'-O-[(S)-{difluoro[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}(hydroxy)phosphoryl]adenosine (C11 H16 F2 N5 O11 P3, 525.2 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site…

Component
F3A
Formula
C11 H16 F2 N5 O11 P3
Class
ligand
Structures
2
PDB entries
1

Binding sites

F3A in 2 structures; the first of them:

  • 3TFR · Ternary complex structure of DNA polymerase beta with a gapped DNA substrate and a, b… · F3A A338 · binds ARG149, GLY179, SER180, ARG183, SER188, GLY189, ASP190, ASP192 and 11 more
  • 3TFR · Ternary complex structure of DNA polymerase beta with a gapped DNA substrate and a, B… · F3A A338 · binds ARG149, GLY179, SER180, ARG183, SER188, GLY189, ASP190, ASP192 and 11 more

Residues it binds most

ARG 2, ASP 2, GLY 2, SER 2, ASN 2, DC 2, DG 2, DT 2, PHE 2, THR 2 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion
  • NA · Sodium ion
  • CL · Chloride ion

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