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Ligand · F2N

F2N · [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2R,3S,4S)-5-[7,8-dimethyl-2,4-dioxo-5-(3-phenylpropanoyl)-1,3,4,5-tetrahydrobenzo[g]pteridin-10(2H)-yl]-2,3,4-trihydroxypentyl dihydrogen diphosphate

F2N, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2R,3S,4S)-5-[7,8-dimethyl-2,4-dioxo-5-(3-phenylpropanoyl)-1,3,4,5-tetrahydrobenzo[g]pteridin-10(2H)-yl]-2,3,4-trihydroxypentyl dihydrogen diphosphate…

Component
F2N
Formula
C36 H43 N9 O16 P2
Class
ligand
Structures
4
PDB entries
2

Binding sites

F2N in 4 structures; the first of them:

  • 2EJR · LSD1-tranylcypromine complex · F2N A1 · binds ILE284, GLY285, SER286, GLY287, VAL288, SER289, GLY290, LEU307 and 36 more
  • 2Z3Y · Crystal structure of Lysine-specific demethylase1 · F2N A1 · binds ILE284, GLY285, SER286, GLY287, VAL288, SER289, GLY290, LEU307 and 35 more
  • 2EJR · LSD1-tranylcypromine complex · F2N A1 · binds ILE284, GLY285, SER286, GLY287, VAL288, SER289, GLY290, LEU307 and 36 more
  • 2Z3Y · Crystal structure of lysine-specific DEMETHYLASE1 · F2N A1 · binds ILE284, GLY285, SER286, GLY287, VAL288, SER289, GLY290, LEU307 and 35 more

Residues it binds most

GLY 4, VAL 4, ALA 4, LEU 4, THR 4, ARG 4, SER 4, GLU 4, TRP 4, ILE 4 (residue and the binding sites it lines).

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