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Ligand · F16

F16 · 5-(3-hydroxyphenyl)isothiazol-3(2H)-one 1,1-dioxide

F16, 5-(3-hydroxyphenyl)isothiazol-3(2H)-one 1,1-dioxide (C9 H7 N O4 S, 225.2 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it binds most…

Component
F16
Formula
C9 H7 N O4 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

F16 in 2 structures; the first of them:

  • 2CM8 · Structural Basis for Inhibition of Protein Tyrosine Phosphatase 1B by Isothiazolidi… · F16 A1299 · binds TYR46, ASP48, VAL49, ASP181, PHE182, GLY183, CYS215, SER216 and 7 more
  • 2CM8 · Structural basis for inhibition of protein tyrosine phosphatase 1B by isothiazolidinone… · F16 A1299 · binds TYR46, ASP48, VAL49, ASP181, PHE182, GLY183, CYS215, SER216 and 7 more

Residues it binds most

GLY 2, ASP 2, GLN 2, ALA 2, ARG 2, CYS 2, ILE 2, PHE 2, SER 2, TYR 2 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion

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