Ligand · EZV
EZV · 4-{3-[7-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-indazol-6-yl}aniline
EZV, 4-{3-[7-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-indazol-6-yl}aniline (C25 H25 N7, 423.5 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å…
- Component
- EZV
- Formula
- C25 H25 N7
- Class
- ligand
- Structures
- 4
- PDB entries
- 2
Binding sites
EZV in 4 structures; the first of them:
- 3EZV · CDK-2 with indazole inhibitor 9 bound at its active site · EZV A300 · binds ILE10, VAL18, ALA31, LYS33, VAL64, PHE80, GLU81, PHE82 and 9 more
- 3F5X · CDK-2-Cyclin complex with indazole inhibitor 9 bound at its active site · EZV A300 · binds ILE10, VAL18, ALA31, LYS33, GLU51, LEU55, VAL64, PHE80 and 12 more
- 3EZV · Cdk-2 with indazole inhibitor 9 bound at its active site · EZV A300 · binds ILE10, VAL18, ALA31, LYS33, VAL64, PHE80, GLU81, PHE82 and 9 more
- 3F5X · Cdk-2-cyclin complex with indazole inhibitor 9 bound at its active site · EZV A300 · binds ILE10, VAL18, ALA31, LYS33, GLU51, LEU55, VAL64, PHE80 and 12 more
Residues it binds most
PHE 6, LEU 6, ALA 6, ASP 6, GLN 6, VAL 6, GLU 6, LYS 6, HIS 6, ILE 6 (residue and the binding sites it lines).
Found with
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