Ligand · EZR

EZR · 3-methoxy-4-{3-[4-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-indazol-6-yl}aniline

EZR, 3-methoxy-4-{3-[4-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-indazol-6-yl}aniline (C26 H27 N7 O, 453.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within…

Component: EZR
Formula: C26 H27 N7 O
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

EZR in 2 structures; the first of them:

3EZR · CDK-2 with indazole inhibitor 17 bound at its active site · EZR A300 · binds ILE10, ALA31, LYS33, VAL64, PHE80, GLU81, PHE82, LEU83 and 9 more
3EZR · Cdk-2 with indazole inhibitor 17 bound at its active site · EZR A300 · binds ILE10, ALA31, LYS33, VAL64, PHE80, GLU81, PHE82, LEU83 and 9 more

Residues it binds most

LEU 4, PHE 2, ALA 2, ASP 2, GLN 2, GLU 4, LYS 2, GLY 2, HIS 2, ILE 2 (residue and the binding sites it lines).

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