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Ligand · EZF

EZF · Methyl 4-[[4-[[3-[4-(aminomethyl)phenyl]-2-methyl-7-oxidanylidene-pyrazolo[4,3-d]pyrimidin-6-yl]methyl]-4-oxidanyl-piperidin-1-yl]methyl]-3-chloranyl-benzoate

EZF, Methyl 4-[[4-[[3-[4-(aminomethyl)phenyl]-2-methyl-7-oxidanylidene-pyrazolo[4,3-d]pyrimidin-6-yl]methyl]-4-oxidanyl-piperidin-1-yl]methyl]-3-chloranyl-benzoate (C28 H31 Cl N6 O4, 551.0 g/mol), in the MolNFT structures on GenesisL1…

Component
EZF
Formula
C28 H31 Cl N6 O4
Class
ligand
Structures
1
PDB entries
1

Binding sites

EZF in 1 structure; the first of them:

  • 6M1K · USP7 in complex with a novel inhibitor · EZF A601 · binds TYR224, ASP295, VAL296, GLN297, GLN351, LEU406, MET407, ARG408 and 11 more

Residues it binds most

TYR 2, ASN 2, ASP 2, GLN 2, HIS 2, MET 2, ARG 2, ILE 2, LEU 2, LYS 2 (residue and the binding sites it lines).

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