Ligand · EZF

EZF · methyl 4-[[4-[[3-[4-(aminomethyl)phenyl]-2-methyl-7-oxidanylidene-pyrazolo[4,3-d]pyrimidin-6-yl]methyl]-4-oxidanyl-piperidin-1-yl]methyl]-3-chloranyl-benzoate

EZF, methyl 4-[[4-[[3-[4-(aminomethyl)phenyl]-2-methyl-7-oxidanylidene-pyrazolo[4,3-d]pyrimidin-6-yl]methyl]-4-oxidanyl-piperidin-1-yl]methyl]-3-chloranyl-benzoate (C28 H31 Cl N6 O4, 551.0 g/mol), in the MolNFT structures on GenesisL1…

Component: EZF
Formula: C28 H31 Cl N6 O4
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

EZF in 2 structures; the first of them:

6M1K · USP7 in complex with a novel inhibitor · EZF A601 · binds TYR224, ASP295, VAL296, GLN297, GLN351, GLN405, LEU406, MET407 and 12 more
6M1K · USP7 in complex with a novel inhibitor · EZF A601 · binds TYR224, ASP295, VAL296, GLN297, GLN351, LEU406, MET407, ARG408 and 11 more

Residues it binds most

TYR 4, GLN 4, ASN 4, ASP 4, HIS 4, MET 4, ARG 4, ILE 4, LEU 4, LYS 4 (residue and the binding sites it lines).

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