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Ligand · EX4

EX4 · (5R)-4-(4-{4-[4-fluoro-3-(trifluoromethyl)phenyl]-1-[2-(pyrrolidin-1-yl)ethyl]-1H-imidazol-2-yl}piperidin-1-yl)-5-methyl-5,8-dihydropyrido[2,3-d]pyrimidin-7(6H)-one

EX4, (5R)-4-(4-{4-[4-fluoro-3-(trifluoromethyl)phenyl]-1-[2-(pyrrolidin-1-yl)ethyl]-1H-imidazol-2-yl}piperidin-1-yl)-5-methyl-5,8-dihydropyrido[2,3-d]pyrimidin-7(6H)-one (C29 H33 F4 N7 O, 571.6 g/mol), in the MolNFT structures on…

Component
EX4
Formula
C29 H33 F4 N7 O
Class
ligand
Structures
1
PDB entries
1

Binding sites

EX4 in 1 structure; the first of them:

  • 6CCY · Crystal structure of AKT1 in complex with a selective inhibitor · EX4 A501 · binds LEU156, GLY157, LYS158, GLY159, THR160, PHE161, GLY162, LYS163 and 14 more

Residues it binds most

GLU 1, GLY 1, LYS 1, PHE 1, ALA 1, LEU 1, MET 1, THR 1, TYR 1, VAL 1 (residue and the binding sites it lines).

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