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Ligand · EWZ

EWZ · 5-{[(4-tert-butyl-6-oxo-1,6-dihydropyrimidin-2-yl)sulfanyl]acetyl}-2-chlorobenzenesulfonamide

EWZ, 5-{[(4-tert-butyl-6-oxo-1,6-dihydropyrimidin-2-yl)sulfanyl]acetyl}-2-chlorobenzenesulfonamide (C16 H18 Cl N3 O4 S2, 415.9 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…

Component
EWZ
Formula
C16 H18 Cl N3 O4 S2
Class
ligand
Structures
2
PDB entries
1

Binding sites

EWZ in 2 structures; the first of them:

  • 4QSI · Crystal structure of human carbonic anhydrase isozyme II with… · EWZ A305 · binds TRP5, ASN62, HIS64, ASN67, GLN92, HIS94, HIS96, GLU106 and 12 more
  • 4QSI · Crystal structure of human carbonic anhydrase isozyme II with 5-{[(4… · EWZ A305 · binds TRP5, ASN62, HIS64, ASN67, GLN92, HIS94, HIS96, GLU106 and 12 more

Residues it binds most

HIS 2, ASN 2, LEU 2, PRO 2, THR 2, TRP 2, VAL 2, GLN 2, GLU 2, PHE 2 (residue and the binding sites it lines).

Found with

  • NA · Sodium ion
  • ZN · Zinc ion
  • DMS · Dimethyl sulfoxide
  • MES · 2-(N-morpholino)-ethanesulfonic acid

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