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Ligand · EWY

EWY · 3-{[(4-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)sulfanyl]acetyl}benzenesulfonamide

EWY, 3-{[(4-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)sulfanyl]acetyl}benzenesulfonamide (C13 H13 N3 O4 S2, 339.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5…

Component
EWY
Formula
C13 H13 N3 O4 S2
Class
ligand
Structures
2
PDB entries
1

Binding sites

EWY in 2 structures; the first of them:

  • 4QSB · Crystal structure of human carbonic anhydrase isozyme II with… · EWY A302 · binds ILE91, GLN92, HIS94, HIS96, GLU106, HIS119, VAL121, PHE131 and 6 more
  • 4QSB · Crystal structure of human carbonic anhydrase isozyme II with 3-{[(4… · EWY A302 · binds ILE91, GLN92, HIS94, HIS96, GLU106, HIS119, VAL121, PHE131 and 6 more

Residues it binds most

HIS 2, THR 2, VAL 2, GLN 2, GLU 2, ILE 2, LEU 2, PHE 2, SER 2, TRP 2 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion
  • DMS · Dimethyl sulfoxide
  • MES · 2-(N-morpholino)-ethanesulfonic acid

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