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Ligand · EUY

EUY · (2R)-N-hydroxy-2-methyl-2-(methylsulfonyl)-4-{2-oxo-4-[4-(2H-1,2,3-triazol-2-yl)phenyl]pyridin-1(2H)-yl}butanamide

EUY, (2R)-N-hydroxy-2-methyl-2-(methylsulfonyl)-4-{2-oxo-4-[4-(2H-1,2,3-triazol-2-yl)phenyl]pyridin-1(2H)-yl}butanamide (C19 H21 N5 O5 S, 431.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding…

Component
EUY
Formula
C19 H21 N5 O5 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

EUY in 2 structures; the first of them:

  • 6CAX · Crystal structure of LpxC from Pseudomonas aeruginosa in complex with PT805 · EUY A401 · binds LEU18, HIS19, MET62, GLU77, HIS78, THR190, PHE191, GLY192 and 13 more
  • 6CAX · Crystal structure of lpxc from pseudomonas aeruginosa in complex with PT805 · EUY A401 · binds LEU18, HIS19, MET62, GLU77, HIS78, THR190, PHE191, GLY192 and 11 more

Residues it binds most

SER 4, PHE 4, HIS 2, GLY 4, ILE 4, LEU 4, MET 4, ALA 4, THR 4, TYR 2 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion
  • CL · Chloride ion
  • EDO · 1,2-ethanediol

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