GL1X · GenesisL1 explorer

Ligand · EUX

EUX · N-[2-(1-cyclopropylsulfonylpyrazol-4-yl)pyrimidin-4-yl]-7-(4-methylpiperazin-1-yl)-5-propan-2-yl-9-[2,2,2-tris(fluoranyl)ethoxy]pyrido[4,3-b]indol-3-amine

EUX, N-[2-(1-cyclopropylsulfonylpyrazol-4-yl)pyrimidin-4-yl]-7-(4-methylpiperazin-1-yl)-5-propan-2-yl-9-[2,2,2-tris(fluoranyl)ethoxy]pyrido[4,3-b]indol-3-amine (C31 H34 F3 N9 O3 S, 669.7 g/mol), in the MolNFT structures on GenesisL1: bound…

Component
EUX
Formula
C31 H34 F3 N9 O3 S
Class
ligand
Structures
1
PDB entries
1

Binding sites

EUX in 1 structure; the first of them:

  • 6LUB · Crystal structure of EGFR(L858R/T790M/C797S) in complex with CH7233163 · EUX A1101 · binds LEU718, VAL726, LYS728, ALA743, LYS745, CYS775, MET790, GLN791 and 9 more

Residues it binds most

LEU 1, LYS 1, MET 1, ALA 1, ARG 1, ASN 1, ASP 1, CYS 1, GLN 1, GLY 1 (residue and the binding sites it lines).

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