Ligand · EUW
EUW · 2-[[2-[[4-[[[3,4-bis(oxidanylidene)-2-[2-(propanoylamino)ethylamino]cyclobuten-1-yl]amino]methyl]phenyl]amino]-5-chloranyl-pyrimidin-4-yl]amino]-~{N}-methyl-benzamide
EUW, 2-[[2-[[4-[[[3,4-bis(oxidanylidene)-2-[2-(propanoylamino)ethylamino]cyclobuten-1-yl]amino]methyl]phenyl]amino]-5-chloranyl-pyrimidin-4-yl]amino]-~{N}-methyl-benzamide (C28 H29 Cl N8 O4, 577.0 g/mol), in the MolNFT structures on…
- Component
- EUW
- Formula
- C28 H29 Cl N8 O4
- Class
- ligand
- Structures
- 3
- PDB entries
- 2
Binding sites
EUW in 3 structures; the first of them:
- 6GCR · Focal Adhesion Kinase catalytic domain in complex with irreversible inhibitor · EUW A701 · binds ARG426, CYS427, ILE428, GLY429, GLU430, VAL436, GLN438, ALA452 and 13 more
- 6GCR · Focal adhesion kinase catalytic domain in complex with irreversible inhibitor · EUW A701 · binds ARG426, CYS427, ILE428, GLY429, VAL436, ALA452, GLU500, LEU501 and 9 more
- 6GCX · Focal adhesion kinase catalytic domain in complex with irreversible inhibitor · EUW A701 · binds ARG426, CYS427, ILE428, VAL436, GLN438, ALA452, VAL484, MET499 and 12 more
Residues it binds most
LEU 3, GLY 3, CYS 3, GLU 3, VAL 3, ALA 3, ARG 3, ASN 3, ASP 3, ILE 3 (residue and the binding sites it lines).
Found with
- SO4 · Sulfate ion
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