GL1X · GenesisL1 explorer

Ligand · ET8

ET8 · 3-phenyl-5-(pyridin-4-yl)-1H-indazole

ET8, 3-phenyl-5-(pyridin-4-yl)-1H-indazole (C18 H13 N3, 271.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands…

Component
ET8
Formula
C18 H13 N3
Class
ligand
Structures
2
PDB entries
1

Binding sites

ET8 in 2 structures; the first of them:

  • 6CJH · Co-crystal structure of MNK2 in complex with an inhibitor · ET8 A402 · binds LEU90, GLY91, ALA111, LYS113, LEU143, PHE159, GLY165, SER166 and 5 more
  • 6CJH · Co-crystal structure of MNK2 in complex with an inhibitor · ET8 A402 · binds LEU90, GLU209, LEU212, CYS225, ASP226

Residues it binds most

LEU 2, ASP 2, CYS 2, GLU 2, GLY 1, ALA 1, ASN 1, LYS 1, PHE 1, SER 1 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.