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Ligand · EP9

EP9 · N-[(benzyloxy)carbonyl]-L-leucyl-N-[(2S,3S)-3-hydroxy-1-(4-hydroxyphenyl)-4-oxobutan-2-yl]-L-leucinamide

EP9, N-[(benzyloxy)carbonyl]-L-leucyl-N-[(2S,3S)-3-hydroxy-1-(4-hydroxyphenyl)-4-oxobutan-2-yl]-L-leucinamide (C30 H41 N3 O7, 555.7 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with…

Component
EP9
Formula
C30 H41 N3 O7
Class
ligand
Structures
2
PDB entries
1

Binding sites

EP9 in 2 structures; the first of them:

  • 3OKJ · Alpha-keto-aldehyde binding mechanism reveals a novel lead structure motif for proteasome… · EP9 K300 · binds THR1, ARG19, ALA20, THR21, ALA22, GLY23, ALA27, VAL31 and 12 more
  • 3OKJ · Alpha-keto-aldehyde binding mechanism reveals a novel lead structure motif for proteasome… · EP9 K300 · binds THR1, ARG19, ALA20, THR21, ALA22, GLY23, ALA27, VAL31 and 12 more

Residues it binds most

ALA 4, GLY 4, SER 4, THR 4, ARG 4, ASP 4, GLN 4, GLU 4, LYS 4, MET 4 (residue and the binding sites it lines).

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