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Ligand · EP4

EP4 · 5'-deoxy-5'-(dimethylamino)adenosine

EP4, 5'-deoxy-5'-(dimethylamino)adenosine (C12 H18 N6 O3, 294.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands…

Component
EP4
Formula
C12 H18 N6 O3
Class
ligand
Structures
2
PDB entries
1

Binding sites

EP4 in 2 structures; the first of them:

  • 4EK9 · Crystal structure of DOT1L in complex with EPZ000004 · EP4 A501 · binds PRO133, GLU134, VAL135, TYR136, GLY137, GLY163, GLY165, VAL185 and 9 more
  • 4EK9 · Crystal structure of DOT1L in complex with EPZ000004 · EP4 A501 · binds PRO133, GLU134, VAL135, TYR136, GLY137, GLY163, GLY165, VAL185 and 9 more

Residues it binds most

GLY 2, GLU 2, PHE 2, PRO 2, VAL 2, ALA 2, ASN 2, ASP 2, LYS 2, TYR 2 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion
  • GOL · Glycerol

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