GL1X · GenesisL1 explorer

Ligand · EMK

EMK · (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-[(3,4,6-trideoxy-3-{[3-(1-{(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl}-1H-1,2,3-triazol-4-yl)propyl](methyl)amino}-beta-D-xylo-hexopyranosyl)oxy]-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside

EMK, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-[(3,4,6-trideoxy-3-{[3-(1-{(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl}-1H-1,2,3-triazol-4-yl)propyl](methyl…

Component
EMK
Formula
C52 H88 F N5 O15 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

EMK in 2 structures; the first of them:

  • 3OW2 · Crystal Structure of Enhanced Macrolide Bound to 50S Ribosomal Subunit · EMK 08163 · binds C839, A841, A2099, A2100, G2102, A2103, A2486, C2487 and 9 more
  • 3OW2 · Crystal structure of enhanced macrolide bound to 50S ribosomal subunit · EMK 08163 · binds C839, A841, A2099, A2100, G2102, A2103, A2486, C2487 and 9 more

Residues it binds most

A 2, U 2, C 2, G 2, MET 2 (residue and the binding sites it lines).

Found with

  • CD · Cadmium ion
  • K · Potassium ion
  • MG · Magnesium ion
  • NA · Sodium ion
  • SR · Strontium ion
  • CL · Chloride ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.