GL1X · GenesisL1 explorer

Ligand · EKR

EKR · N-(2,3-dihydro-1-benzofuran-7-ylmethyl)-8-[4-[(dimethylamino)methyl]phenyl]-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine

EKR, N-(2,3-dihydro-1-benzofuran-7-ylmethyl)-8-[4-[(dimethylamino)methyl]phenyl]-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine (C23 H24 N6 O, 400.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding…

Component
EKR
Formula
C23 H24 N6 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

EKR in 2 structures; the first of them:

  • 7QJG · EED in complex with PRC2 allosteric inhibitor compound 6 · EKR A503 · binds PRO95, PHE97, TYR148, ASN194, LYS211, LEU240, ASP310, TYR365 and 3 more
  • 7QJG · Eed in complex with PRC2 allosteric inhibitor compound 6 · EKR A503 · binds PRO95, PHE97, TYR148, ASN194, LYS211, LEU240, ASP310, TYR365 and 3 more

Residues it binds most

ARG 4, TYR 4, ASP 4, ASN 4, LEU 4, LYS 4, MET 4, PHE 4, PRO 4 (residue and the binding sites it lines).

Found with

  • CL · Chloride ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.