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Ligand · EJZ

EJZ · 5-nitro-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid

EJZ, 5-nitro-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid (C5 H3 N3 O6, 201.1 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it…

Component
EJZ
Formula
C5 H3 N3 O6
Class
ligand
Structures
2
PDB entries
1

Binding sites

EJZ in 2 structures; the first of them:

  • 3MHU · Crystal structure of dihydroorotate dehydrogenase from Leishmania major in complex with… · EJZ A314 · binds LYS44, SER45, ASN68, SER69, MET70, GLY71, LEU72, PRO73 and 6 more
  • 3MHU · Crystal structure of dihydroorotate dehydrogenase from leishmania major in complex with… · EJZ A314 · binds LYS44, SER45, ASN68, SER69, MET70, GLY71, LEU72, PRO73 and 6 more

Residues it binds most

SER 4, ASN 4, PRO 4, CYS 4, GLY 4, LEU 4, LYS 4, MET 4 (residue and the binding sites it lines).

Found with

  • FMN · Flavin mononucleotide
  • SO4 · Sulfate ion
  • GOL · Glycerol

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