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Ligand · EIP

EIP · 4-hydroxy-3-methyl butyl diphosphate

EIP, 4-hydroxy-3-methyl butyl diphosphate (C5 H14 O8 P2, 264.1 g/mol), in the MolNFT structures on GenesisL1: bound in 11 records (6 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the…

Component
EIP
Formula
C5 H14 O8 P2
Class
ligand
Structures
11
PDB entries
6

Binding sites

EIP in 11 structures; the first of them:

  • 1NFZ · Structure and mechanism of action of isopentenylpyrophosphate-dimethylallylpyrophosphate… · EIP A301 · binds LYS21, ALA34, PHE35, ARG51, LYS55, CYS67, GLY68, HIS69 and 8 more
  • 1OW2 · Structure and mechanism of action of isopentenylpyrophosphate-dimethylallylpyrophosphate… · EIP A301 · binds GLU4, LYS21, ALA34, PHE35, ARG51, LYS55, ALA67, GLY68 and 8 more
  • 1PPW · Isopentenylpyrophosphate-dimethylallylpyrophosphate isomerase in complex with the… · EIP A301 · binds GLU4, LYS21, ALA34, PHE35, SER36, ARG51, LYS55, CYS67 and 11 more
  • 2B2K · structure of Y104F IDI-1 mutant in complex with EIPP · EIP A401 · binds GLU4, LYS21, ALA34, PHE35, ARG51, LYS55, CYS67, GLY68 and 9 more
  • 2G73 · Y104F mutant type 1 IPP isomerase complex with EIPP · EIP A186 · binds GLU4, LYS21, ALA34, PHE35, ARG51, LYS55, CYS67, GLY68 and 9 more
  • 3KE8 · Crystal structure of IspH:HMBPP-complex · EIP A998 · binds VAL15, VAL40, HIS41, ALA73, HIS74, VAL99, HIS124, GLU126 and 8 more
  • 1NFZ · Structure and mechanism of action of isopentenylpyrophosphate- dimethylallylpyrophosphate… · EIP A301 · binds LYS21, ALA34, PHE35, ARG51, LYS55, CYS67, GLY68, HIS69 and 8 more
  • 1OW2 · Structure and mechanism of action of isopentenylpyrophosphate- dimethylallylpyrophosphate… · EIP A301 · binds GLU4, LYS21, ALA34, PHE35, ARG51, LYS55, ALA67, GLY68 and 8 more
  • 1PPW · Isopentenylpyrophosphate-dimethylallylpyrophosphate isomerase in complex with the… · EIP A301 · binds GLU4, LYS21, ALA34, PHE35, SER36, ARG51, LYS55, CYS67 and 11 more
  • 2B2K · Structure of Y104F idi-1 mutant in complex with eipp · EIP A401 · binds GLU4, LYS21, ALA34, PHE35, ARG51, LYS55, CYS67, GLY68 and 9 more
  • 2G73 · Y104F mutant type 1 ipp isomerase complex with eipp · EIP A186 · binds GLU4, LYS21, ALA34, PHE35, ARG51, LYS55, CYS67, GLY68 and 9 more

Residues it binds most

GLU 22, ARG 20, LYS 20, CYS 20, ALA 22, PHE 20, HIS 22, GLY 20, TRP 18, SER 6 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion
  • MN · Manganese (II) ion
  • SF4 · Iron/sulfur cluster

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