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Ligand · EII

EII · 3-(2-{3-[(2,4-diamino-6-cyclohexylpyrimidin-5-yl)oxy]propoxy}phenyl)propanoic acid

EII, 3-(2-{3-[(2,4-diamino-6-cyclohexylpyrimidin-5-yl)oxy]propoxy}phenyl)propanoic acid (C22 H30 N4 O4, 414.5 g/mol), in the MolNFT structures on GenesisL1: bound in 1 record (1 PDB entry). Every binding site with its residues within 4.5…

Component
EII
Formula
C22 H30 N4 O4
Class
ligand
Structures
1
PDB entries
1

Binding sites

EII in 1 structure; the first of them:

  • 8TA1 · Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in… · EII A203 · binds ILE7, TRP8, ALA9, ILE22, ASP29, LEU30, HIS32, PHE33 and 11 more

Residues it binds most

ILE 1, LEU 1, HIS 1, PRO 1, THR 1, ALA 1, ARG 1, ASP 1, LYS 1, PHE 1 (residue and the binding sites it lines).

Found with

  • NAP · Nadp nicotinamide-adenine-dinucleotide phosphate
  • NA · Sodium ion
  • ACT · Acetate ion
  • PG4 · Tetraethylene glycol

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