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Ligand · EIF

EIF · [(2~{R},3~{R},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-4-fluoranyl-4-methyl-3-oxidanyl-oxolan-2-yl]methyl dihydrogen phosphate

EIF, [(2~{R},3~{R},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-4-fluoranyl-4-methyl-3-oxidanyl-oxolan-2-yl]methyl dihydrogen phosphate (C11 H15 F N5 O7 P, 379.2 g/mol), in the MolNFT structures on GenesisL1: bound in 2…

Component
EIF
Formula
C11 H15 F N5 O7 P
Class
ligand
Structures
2
PDB entries
2

Binding sites

EIF in 2 structures; the first of them:

  • 8PTS · human GUK1 in complex with compound AT8001 · EIF A201 · binds SER37, ARG41, ARG44, TYR53, GLU72, HIS73, ALA74, PHE76 and 5 more
  • 8QCH · Human Adenosine deaminase-like protein in complex with compound AT8001 · EIF A401 · binds HIS26, LEU27, ASN28, GLY29, PHE67, PHE70, HIS74, ARG105 and 13 more

Residues it binds most

HIS 10, SER 10, ASP 8, ARG 10, GLY 10, PHE 10, TYR 10, GLU 10, LEU 8, THR 10 (residue and the binding sites it lines).

Found with

  • NA · Sodium ion
  • ZN · Zinc ion
  • SO4 · Sulfate ion
  • GOL · Glycerol
  • PEG · Di(hydroxyethyl)ether

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