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Ligand · EIA

EIA · (1Z,3E,5S,7R,8R,10R,11R,12S,15R,16S,18Z,25S)-11-ethyl-2-hydroxy-10-methyl-21,26-diazapentacyclo[23.2.1.05,16.07,15.08,12]octacosa-1(2),3,13,18-tetraene-20,27,28-trione

EIA, (1Z,3E,5S,7R,8R,10R,11R,12S,15R,16S,18Z,25S)-11-ethyl-2-hydroxy-10-methyl-21,26-diazapentacyclo[23.2.1.05,16.07,15.08,12]octacosa-1(2),3,13,18-tetraene-20,27,28-trione (C29 H38 N2 O4, 478.6 g/mol), in the MolNFT structures on…

Component
EIA
Formula
C29 H38 N2 O4
Class
ligand
Structures
2
PDB entries
2

Binding sites

EIA in 2 structures; the first of them:

  • 8JNP · Crystal structure of cytochrome P450 CftA from Streptomyces torulosus NRRL B-3889, in… · EIA A401 · binds ARG72, ARG74, VAL76, ALA77, ARG78, PHE84, TRP164, VAL168 and 8 more
  • 8JOO · Crystal structure of cytochrome P450 IkaD from Streptomyces sp. ZJ306, in complex with… · EIA A502 · binds ARG86, ALA89, ARG90, VAL91, GLY92, PHE96, ILE180, LEU181 and 13 more

Residues it binds most

ARG 3, LEU 3, SER 3, PHE 3, ALA 3, ILE 3, VAL 3, ASP 2, GLY 2, MET 2 (residue and the binding sites it lines).

Found with

  • HEM · Protoporphyrin IX containing Fe
  • NA · Sodium ion
  • FMT · Formic acid

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