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Ligand · EFW

EFW · 6-{[(1R,3R)-3-hydroxycyclopentyl]amino}pyridine-3-carboxamide

EFW, 6-{[(1R,3R)-3-hydroxycyclopentyl]amino}pyridine-3-carboxamide (C11 H15 N3 O2, 221.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it…

Component
EFW
Formula
C11 H15 N3 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

EFW in 2 structures; the first of them:

  • 4YQC · Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds · EFW A301 · binds TYR86, LEU87, SER88, PRO89, GLY113, ARG114, TYR115, GLU116 and 12 more
  • 4YQC · Crystal structure of trmd, a M1G37 tRNA methyltransferase with SAM- competitive compounds · EFW A301 · binds TYR86, LEU87, SER88, PRO89, GLY113, ARG114, TYR115, GLU116 and 12 more

Residues it binds most

GLY 2, TYR 2, LEU 2, PRO 2, SER 2, ARG 2, GLU 2, ILE 2, THR 2, TRP 2 (residue and the binding sites it lines).

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