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Ligand · EFT

EFT · (2R)-3-cyclohexyl-2-(6-hydroxy-1H-indazol-3-yl)propanenitrile

EFT, (2R)-3-cyclohexyl-2-(6-hydroxy-1H-indazol-3-yl)propanenitrile (C16 H19 N3 O, 269.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it…

Component
EFT
Formula
C16 H19 N3 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

EFT in 2 structures; the first of them:

  • 4EFT · Hsp90 Alpha N-terminal Domain in Complex with an Inhibitor… · EFT A301 · binds LEU48, ASN51, SER52, ALA55, ASP93, MET98, LEU103, LEU107 and 6 more
  • 4EFT · HSP90 alpha N-terminal domain in complex with an inhibitor 3… · EFT A301 · binds LEU48, ASN51, SER52, ALA55, ASP93, MET98, LEU103, LEU107 and 6 more

Residues it binds most

LEU 2, VAL 2, ALA 2, ASN 2, ASP 2, MET 2, PHE 2, SER 2, THR 2, TRP 2 (residue and the binding sites it lines).

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