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Ligand · ECZ

ECZ · 8-methoxy-2-[4-(trifluoromethyl)phenyl]-3,4-dihydroquinazolin-4-one

ECZ, 8-methoxy-2-[4-(trifluoromethyl)phenyl]-3,4-dihydroquinazolin-4-one (C16 H11 F3 N2 O2, 320.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the…

Component
ECZ
Formula
C16 H11 F3 N2 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

ECZ in 2 structures; the first of them:

  • 4UI6 · Crystal structure of human tankyrase 2 in complex with TA-47 · ECZ A2113 · binds PHE1030, HIS1031, GLY1032, SER1033, PRO1034, PHE1035, ARG1047, HIS1048 and 10 more
  • 4UI6 · Crystal structure of human tankyrase 2 in complex with ta-47 · ECZ A2113 · binds PHE1030, HIS1031, GLY1032, SER1033, PRO1034, PHE1035, ARG1047, HIS1048 and 10 more

Residues it binds most

PHE 4, TYR 4, ALA 4, HIS 4, SER 4, ARG 4, GLU 4, GLY 4, ILE 4, LYS 4 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion
  • SO4 · Sulfate ion
  • GOL · Glycerol

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