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Ligand · EC8

EC8 · N-(7-fluoro-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl)-2-hydroxybenzamide

EC8, N-(7-fluoro-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl)-2-hydroxybenzamide (C16 H9 F4 N3 O4, 383.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues…

Component
EC8
Formula
C16 H9 F4 N3 O4
Class
ligand
Structures
2
PDB entries
1

Binding sites

EC8 in 2 structures; the first of them:

  • 6FZ4 · Structure of GluK1 ligand-binding domain in complex with… · EC8 A307 · binds GLU13, TYR16, TYR61, PRO88, LEU89, THR90, ARG95, ASP139 and 4 more
  • 6FZ4 · Structure of GLUK1 ligand-binding domain in complex with N-(7-fluoro… · EC8 A307 · binds GLU13, TYR16, TYR61, PRO88, LEU89, THR90, ARG95, ASP139 and 4 more

Residues it binds most

TYR 2, THR 2, ARG 2, ASP 2, GLU 2, GLY 2, LEU 2, PRO 2, SER 2 (residue and the binding sites it lines).

Found with

  • CL · Chloride ion
  • SO4 · Sulfate ion
  • GOL · Glycerol

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