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Ligand · EB7

EB7 · 2-chloro-N-(1-ethyl-2-oxo-1,2-dihydrobenzo[cd]indol-6-yl)-4-fluorobenzenesulfonamide

EB7, 2-chloro-N-(1-ethyl-2-oxo-1,2-dihydrobenzo[cd]indol-6-yl)-4-fluorobenzenesulfonamide (C19 H14 Cl F N2 O3 S, 404.8 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues…

Component
EB7
Formula
C19 H14 Cl F N2 O3 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

EB7 in 2 structures; the first of them:

  • 5CRZ · Crystal Structure of the first bromodomain of human BRD4 in complex with… · EB7 A204 · binds TRP81, PRO82, PHE83, VAL87, LEU92, LEU94, TYR97, CYS136 and 5 more
  • 5CRZ · Crystal structure of the first bromodomain of human BRD4 in complex with… · EB7 A204 · binds TRP81, PRO82, PHE83, VAL87, LEU92, LEU94, TYR97, CYS136 and 5 more

Residues it binds most

LEU 2, TYR 2, ASN 2, ASP 2, CYS 2, ILE 2, MET 2, PHE 2, PRO 2, TRP 2 (residue and the binding sites it lines).

Found with

  • NO3 · Nitrate ion
  • EDO · 1,2-ethanediol
  • GOL · Glycerol

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