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Ligand · EAZ

EAZ · (2~{S})-4-methyl-1-[5-(3-methyl-2~{H}-indazol-5-yl) pyridin-3-yl]oxy-pentan-2-amine

EAZ, (2~{S})-4-methyl-1-[5-(3-methyl-2~{H}-indazol-5-yl) pyridin-3-yl]oxy-pentan-2-amine (C19 H24 N4 O, 324.4 g/mol), in the MolNFT structures on GenesisL1: bound in 1 record (1 PDB entry). Every binding site with its residues within 4.5…

Component
EAZ
Formula
C19 H24 N4 O
Class
ligand
Structures
1
PDB entries
1

Binding sites

EAZ in 1 structure; the first of them:

  • 6FYK · X-ray structure of CLK2-KD(136-496)/INDAZOLE1 at 2.39A · EAZ A501 · binds LEU169, GLU171, PHE174, ALA191, LYS193, VAL227, PHE243, GLU244 and 7 more

Residues it binds most

LEU 3, GLU 3, VAL 3, PHE 3, ALA 3, ASN 3, ASP 3, LYS 3 (residue and the binding sites it lines).

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