GL1X · GenesisL1 explorer

Ligand · EAQ

EAQ · 6-~{tert}-butyl-~{N}-[6-(1~{H}-pyrazol-4-yl)-1~{H}-imidazo[1,2-a]pyridin-2-yl]pyridine-3-carboxamide

EAQ, 6-~{tert}-butyl-~{N}-[6-(1~{H}-pyrazol-4-yl)-1~{H}-imidazo[1,2-a]pyridin-2-yl]pyridine-3-carboxamide (C20 H21 N6 O, 361.4 g/mol), in the MolNFT structures on GenesisL1: bound in 3 records (2 PDB entries). Every binding site with its…

Component
EAQ
Formula
C20 H21 N6 O
Class
ligand
Structures
3
PDB entries
2

Binding sites

EAQ in 3 structures; the first of them:

  • 6FYO · X-RAY STRUCTURE OF CLK1-KD(148-484)/Cpd-2 AT 2.32A · EAQ A501 · binds LEU167, VAL175, ALA189, LYS191, GLU206, VAL225, PHE241, GLU242 and 8 more
  • 6FYO · X-ray structure of CLK1-KD(148-484)/CPD-2 at 2.32A · EAQ A501 · binds LEU167, ALA189, LYS191, GLU206, VAL225, PHE241, GLU242, LEU243 and 7 more
  • 6FYR · X-ray structure of CLK3-KD(GP-[275-632], non-PHOS.)/CPD-2 at 1.42A · EAQ A501 · binds LEU162, ALA184, PHE236, GLU237, LEU238, LEU239, GLY240, LYS241 and 3 more

Residues it binds most

LEU 3, GLU 3, VAL 2, ALA 3, ASP 3, GLY 3, LYS 3, PHE 3, SER 2 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.