GL1X · GenesisL1 explorer

Ligand · E9F

E9F · 4-(6-{1-[(R)-S-methanesulfonimidoyl]cyclopropyl}-2-[(3R)-3-methylmorpholin-4-yl]pyrimidin-4-yl)-1H-pyrrolo[2,3-b]pyridine

E9F, 4-(6-{1-[(R)-S-methanesulfonimidoyl]cyclopropyl}-2-[(3R)-3-methylmorpholin-4-yl]pyrimidin-4-yl)-1H-pyrrolo[2,3-b]pyridine (C20 H24 N6 O2 S, 412.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…

Component
E9F
Formula
C20 H24 N6 O2 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

E9F in 2 structures; the first of them:

  • 7T2I · Crystal structure of the tandem bromodomain (BD1, BD2) of human TAF1 bound to ZS1-588 · E9F A1705 · binds TRP1526, PRO1527, PHE1528, HIS1530, PRO1531, VAL1532, ASN1533, PHE1536 and 5 more
  • 7T2I · Crystal structure of the tandem bromodomain (BD1, BD2) of human TAF1 bound to ZS1-588 · E9F A1705 · binds TRP1526, PRO1527, PHE1528, HIS1530, PRO1531, VAL1532, ASN1533, PHE1536 and 3 more

Residues it binds most

TYR 2, ASN 2, PHE 2, PRO 2, VAL 2, HIS 2, TRP 2 (residue and the binding sites it lines).

Found with

  • DMS · Dimethyl sulfoxide
  • EDO · 1,2-ethanediol

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