Ligand · E72
E72 · 7-[(5-aminopentyl)oxy]-N~4~-[1-(5-aminopentyl)piperidin-4-yl]-N~2~-[3-(dimethylamino)propyl]-6-methoxyquinazoline-2,4-diamine
E72, 7-[(5-aminopentyl)oxy]-N~4~-[1-(5-aminopentyl)piperidin-4-yl]-N~2~-[3-(dimethylamino)propyl]-6-methoxyquinazoline-2,4-diamine (C29 H52 N8 O2, 544.8 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…
- Component
- E72
- Formula
- C29 H52 N8 O2
- Class
- ligand
- Structures
- 2
- PDB entries
- 1
Binding sites
E72 in 2 structures; the first of them:
- 3MO5 · Human G9a-like (GLP, also known as EHMT1) in complex with inhibitor E72 · E72 A1236 · binds TYR1124, ASP1131, ALA1134, ASP1135, VAL1136, ARG1137, GLU1138, ASP1140 and 12 more
- 3MO5 · Human G9A-like (glp, also known as EHMT1) in complex with inhibitor E72 · E72 A1236 · binds TYR1124, ASP1131, ALA1134, ASP1135, VAL1136, ARG1137, GLU1138, ASP1140 and 12 more
Residues it binds most
ASP 8, PHE 8, TYR 8, ARG 8, ALA 8, CYS 8, ILE 8, LEU 8, LYS 8, SER 8 (residue and the binding sites it lines).
Found with
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