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Ligand · E6C

E6C · N-[1-hydroxycarboxyethyl-carbonyl]leucylamino-2-methyl-butane

E6C, N-[1-hydroxycarboxyethyl-carbonyl]leucylamino-2-methyl-butane (C15 H28 N2 O5, 316.4 g/mol), in the MolNFT structures on GenesisL1: bound in 6 records (3 PDB entries). Every binding site with its residues within 4.5 Å, the residues it…

Component
E6C
Formula
C15 H28 N2 O5
Class
ligand
Structures
6
PDB entries
3

Binding sites

E6C in 6 structures; the first of them:

  • 1ITO · Crystal Structure Analysis of Bovine Spleen Cathepsin B-E64c complex · E6C A700 · binds GLN23, CYS26, GLY27, SER28, CYS29, TRP30, GLY68, ASP69 and 10 more
  • 1PE6 · Refined X-ray structure of PAPAIN(DOT)E-64-C complex at 2.1-ångströms resolution · E6C A213 · binds GLN19, CYS22, GLY23, SER24, CYS25, TRP26, TYR61, ASN64 and 7 more
  • 1PPP · Crystal structure of papain-E64-C complex. binding diversity of E64-C to papain S2 and S3… · E6C A213 · binds GLN19, CYS22, GLY23, SER24, CYS25, TRP26, GLY65, GLY66 and 5 more
  • 1ITO · Crystal structure analysis of bovine spleen cathepsin B-E64C complex · E6C A700 · binds GLN23, CYS26, GLY27, SER28, CYS29, TRP30, GLY68, ASP69 and 10 more
  • 1PE6 · Refined X-ray structure of PAPAIN(DOT)E-64-C complex at 2.1-ångströms resolution · E6C A213 · binds GLN19, CYS22, GLY23, SER24, CYS25, TRP26, TYR61, ASN64 and 7 more
  • 1PPP · Crystal structure of papain-E64-C complex. binding diversity of E64-C to papain S2 and S3… · E6C A213 · binds GLN19, CYS22, GLY23, SER24, CYS25, TRP26, GLY65, GLY66 and 5 more

Residues it binds most

GLY 6, CYS 6, ALA 6, ASP 6, GLN 6, HIS 6, SER 6, TRP 6, TYR 4, ASN 4 (residue and the binding sites it lines).

Found with

  • MOH · Methanol

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