GL1X · GenesisL1 explorer

Ligand · E56

E56 · 3-[4-[6-chloranyl-5-[[(3R)-pyrrolidin-3-yl]amino]-1H-indazol-3-yl]pyrazol-1-yl]benzenecarbonitrile

E56, 3-[4-[6-chloranyl-5-[[(3R)-pyrrolidin-3-yl]amino]-1H-indazol-3-yl]pyrazol-1-yl]benzenecarbonitrile (C21 H18 Cl N7, 403.9 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…

Component
E56
Formula
C21 H18 Cl N7
Class
ligand
Structures
2
PDB entries
1

Binding sites

E56 in 2 structures; the first of them:

  • 7DXL · Fragment-based Lead Discovery of Indazole-based Compounds as AXL Kinase Inhibitors · E56 A901 · binds LEU593, VAL601, ALA617, LYS619, MET650, LEU671, PRO672, PHE673 and 8 more
  • 7DXL · Fragment-based lead discovery of indazole-based compounds as axl kinase inhibitors · E56 A901 · binds LEU593, ALA617, MET650, LEU671, PRO672, PHE673, MET674, LYS675 and 6 more

Residues it binds most

MET 4, ALA 4, LEU 4, LYS 4, ARG 4, ASN 4, ASP 4, PHE 4, PRO 4, GLY 3 (residue and the binding sites it lines).

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.