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Ligand · E46

E46 · N-(piperidin-4-ylmethyl)-3-[3-(trifluoromethyloxy)phenyl]-[1,2,3]triazolo[4,5-b]pyridin-5-amine

E46, N-(piperidin-4-ylmethyl)-3-[3-(trifluoromethyloxy)phenyl]-[1,2,3]triazolo[4,5-b]pyridin-5-amine (C18 H19 F3 N6 O, 392.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…

Component
E46
Formula
C18 H19 F3 N6 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

E46 in 2 structures; the first of them:

  • 4A7C · Crystal structure of PIM1 kinase with ETP46546 · E46 A1306 · binds LEU44, GLY45, PHE49, VAL52, ALA65, LYS67, ILE104, LEU120 and 9 more
  • 4A7C · Crystal structure of PIM1 kinase with ETP46546 · E46 A1306 · binds LEU44, GLY45, PHE49, VAL52, ALA65, LYS67, ILE104, LEU120 and 9 more

Residues it binds most

LEU 2, ASP 2, GLU 2, ILE 2, VAL 2, ALA 2, ARG 2, GLY 2, LYS 2, PHE 2 (residue and the binding sites it lines).

Found with

  • ACT · Acetate ion
  • IMD · Imidazole

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