GL1X · GenesisL1 explorer

Ligand · E31

E31 · 2-(4-{[2-(3-chlorophenyl)-6-ethylpyrimidin-4-yl]methyl}phenyl)acetamide

E31, 2-(4-{[2-(3-chlorophenyl)-6-ethylpyrimidin-4-yl]methyl}phenyl)acetamide (C21 H20 Cl N3 O, 365.9 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the…

Component
E31
Formula
C21 H20 Cl N3 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

E31 in 2 structures; the first of them:

  • 6BOJ · Crystal Structure of the PDE4D Catalytic Domain and UCR2 Regulatory Helix with BPN5004 · E31 A703 · binds TYR325, HIS326, HIS370, SER374, MET439, LEU485, ASN487, TYR495 and 13 more
  • 6BOJ · Crystal structure of the PDE4D catalytic domain and UCR2 regulatory helix with BPN5004 · E31 A703 · binds HIS326, SER374, MET439, LEU485, ASN487, TYR495, TRP498, THR499 and 9 more

Residues it binds most

PHE 8, MET 8, ILE 8, SER 8, THR 8, TYR 8, HIS 8, ASN 8, GLN 8, LEU 8 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion
  • ZN · Zinc ion
  • CL · Chloride ion
  • MPD · (4S)-2-methyl-2,4-pentanediol

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.