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Ligand · DXF

DXF · (2R)-5-[(carbamoyloxy)methyl]-2-[(1R)-1-{[(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetyl]amino}-2-oxoethyl]-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid

DXF, (2R)-5-[(carbamoyloxy)methyl]-2-[(1R)-1-{[(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetyl]amino}-2-oxoethyl]-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid (C16 H18 N4 O8 S, 426.4 g/mol), in the MolNFT structures on GenesisL1: bound in 4…

Component
DXF
Formula
C16 H18 N4 O8 S
Class
ligand
Structures
4
PDB entries
2

Binding sites

DXF in 4 structures; the first of them:

  • 3NBL · Crystal Structure of BlaC-E166A covalently bound with Cefuroxime · DXF A1 · binds CYS83, SER84, LYS87, ILE117, SER142, PRO183, THR232, ARG236 and 7 more
  • 3ZG9 · Crystal Structure of Penicillin-Binding Protein 4 from Listeria monocytogenes in the… · DXF A801 · binds GLY393, SER394, LYS397, VAL432, ASN448, SER449, ASN451, LEU488 and 11 more
  • 3NBL · Crystal structure of blac-E166A covalently bound with cefuroxime · DXF A1 · binds CYS83, SER84, LYS87, ILE117, SER142, PRO183, THR232, ARG236 and 7 more
  • 3ZG9 · Crystal structure of penicillin-binding protein 4 from listeria monocytogenes in the… · DXF A801 · binds GLY393, SER394, LYS397, VAL432, ASN448, SER449, ASN451, LEU488 and 11 more

Residues it binds most

THR 4, SER 4, GLY 4, LYS 4, ASN 2, ARG 2, ASP 2, CYS 2, GLN 2, GLU 2 (residue and the binding sites it lines).

Found with

  • GOL · Glycerol

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