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Ligand · DVN

DVN · [[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-3-oxidanyl-4-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2R,3S,4R,5S)-3,4,5-tris(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate

DVN, [[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-3-oxidanyl-4-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2R,3S,4R,5S)-3,4,5-tris(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate (C15 H24 N5 O17 P3, 639.3 g/mol), in the MolNFT…

Component
DVN
Formula
C15 H24 N5 O17 P3
Class
ligand
Structures
2
PDB entries
1

Binding sites

DVN in 2 structures; the first of them:

  • 4F46 · Crystal structure of wild type human CD38 in complex with NAADP and ADPRP · DVN A401 · binds LEU124, TRP125, SER126, ARG127, LYS129, LEU145, GLU146, ASP156 and 9 more
  • 4F46 · Crystal structure of wild type human CD38 in complex with naadp and adprp · DVN A401 · binds LEU124, TRP125, SER126, ARG127, LYS129, LEU145, GLU146, ASP156 and 9 more

Residues it binds most

LEU 2, SER 2, GLU 2, THR 2, TRP 2, ARG 2, ASP 2, LYS 2, PHE 2, VAL 2 (residue and the binding sites it lines).

Found with

  • DN4 · [[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-3-oxidanyl-4-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2R,3S,4R,5R)-5-(3-carboxypyridin-1-ium-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl phosphate

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